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|Yingxin Yu, Bart Blokhuis, Yvonne Derks, Sangeeta Kumari, Johan Garssen & Frank Redegeld (2018) Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models, OncoImmunology, 7:11, e1504729, DOI: 10.1080/2162402X.2018.1504729||
Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.
|Yu Y, Blokhuis BRJ, Diks MAP, Keshavarzian A, Garssen J and Redegeld FA (2018) Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells. Front. Immunol. 9:2138. doi: 10.3389/fimmu.2018.02138||
Mast cells (MC) accumulate in colorectal cancer (CRC) and the relationship between MC density and cancer progression has been well recognized.
|Mezouar, Soraya & Ben Amara, Amira & Vitte, Joana & Mege, Jean‐Louis. (2018). Isolation of Human Placental Mast Cells. Current Protocols in Cell Biology. 80. 10.1002/cpcb.52.||
Mast cells have been identified as resident cells of human placental tissue by immunohistological procedures, suggesting that they may play a role in pregnancy.