COST Action BM1007

Mast Cells and Basophils – Targets for Innovative Therapies

The European Cooperation in Science and Technology (COST) Action BM 1007 on undefinedMast Cells and Basophils – Targets for Innovative Therapies has as its main objective the identification and characterisation of novel disease-related cell specific targets that will result in the development of innovative therapeutic strategies for the treatment of chronic inflammatory and autoimmune diseases.

The Action greatly benefits from the active and enthusiastic members of the European Mast Cell and Basophil Network (EMBRN), which was previously founded as a European platform for mast cell and basophil research.

With its focus on basic, clinical and translational science in mast cell and basophil research across Europe the COST Action is complementary with the EMBRN and fosters a multidisciplinary approach to mast cell and basophil research in order to increase understanding and to translate this knowledge into the development of potentially beneficial end points. Mast cells and basophils have long been recognized for their detrimental role in the elicitation of allergic diseases. In recent years, scientific results revealed both cell types as versatile effector cells that exhibit far more complex functions beyond their role in allergy.

Mast cells and basophils have been shown to be critically involved in various innate and adaptive immune responses and, thereby, providing beneficial host protecting immunity. They also contribute to the development and maintenance of several chronic inflammatory diseases which, even at the present time, lack sufficient treatment options.

The diversity of important mast cell and basophil functions places these cell types into promising therapeutic targets. The COST Action BM 1007 creates a network of experts to foster a multidisciplinary approach for the identification, characterisation, and development of such targets and their translation into novel therapeutic strategies.

For more detailed information about COST and Action BM1007 on Mast Cells and Basophils – Targets for Innovative Therapies please visit

Best regards,

The Management Committee of COST Action BM1007

News & Events

EMBRN volume on mast cells and basophils and their functions is now in press in Immunological Reviews

Immunological Reviews just published a series of reports on mast cells, basophils and their role in health and disease (Immunological Reviews 2018; Vol 82, page 1-277).

Original and review papers on mast cells / basophils wanted!

Our colleagues Thomas Marichal, Nicolas Gaudenzio, Laurent Reber, and Philipp Starkl are putting together, as guest editors, a Special Issue on the regulation of type 2 immunity by mast cells and...

9th EMBRN International Mast Cell and Basophil Meeting in Uppsala, June 17th to 19th, 2019

We are pleased to let you know that the 9th European Mast Cell and Basophil Research Network (EMBRN) meeting is scheduled to be in Uppsala, Sweden from Monday, June 17th to 19th, 2019. Stay tuned for...

Free Access to Recent Articles on Mast Cells and Basophils

Dear Colleague,

Mast cells and basophils are potent effector cells of the innate immune system, and play a significant role in allergy, autoimmune diseases and cancer.

Our Partners